ABSTRACT
Introduction Individuals with affective and anxiety disorders are among those most vulnerable to the negative effects of the COVID-19 pandemic. Aim This study aims to analyze the determinants of stress levels and protective behavioral strategies associated with the COVID-19 pandemic in Russian-speaking people with affective or anxiety disorders (AADs). Materials and Methods In this cross-sectional online survey, the psychological distress and behavioral patterns of respondents with self-reported AAD (n = 1,375) and without disorders (n = 4,278) were evaluated during three periods of restrictive measures in Russia (March–May 2020). Distress levels were verified using the Psychological Stress Measure (PSM-25). Results Stress levels among respondents with AAD were higher at all study periods than for those with no mental disorder (Cohen's d 0.8–1.6). The stress level increased (Cohen's d = 0.4) in adolescents (16–18 years) with AAD and remained the same in those without disorders;in youths (19–24 years) with and without disorders, an increase (Cohen's d = 0.3) and a decrease (Cohen's d = 0.3) in the stress were observed, correspondingly;the stress in adults (25–44 years) with disorders did not change and decreased in those without disorders (Cohen's d = 0.4). Individuals with bipolar disorders demonstrated lower stress than individuals with depressive (Cohen's d = 0.15) and anxiety disorders (Cohen's d = 0.27). Respondents with depressive and bipolar disorders employed fewer protective measures simultaneously and were less likely to search for information about COVID-19. Conclusion The presence of affective or anxiety disorders is associated with a more acute response to the COVID-19 pandemic. Apparently, the type of mental disorder influenced stress levels and protective behavior patterns.